3HA6 - Crystal structure of aurora A in complex with TPX2 and compound 10

Lisa M. Baker; James B. Murray; Roderick E. Hubbard
PDBJ - 8AHI
https://www.rcsb.org/structure/8AHI

Abstract

PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery
PDB DOI: 10.2210/pdb8AHI/pdb
Classification: TRANSFERASE
Organism(s): Homo sapiens
Expression System: Escherichia coli BL21(DE3)
Mutation(s): Yes
Deposited: 2022-07-21 Released: 2022-09-14
Deposition Author(s): Baker, L.M., Murray, J.B., Hubbard, R.E.
Funding Organization(s): Not funded
Experimental Data Snapshot
Method: X-RAY DIFFRACTION
Resolution: 2.69 Å
R-Value Free: 0.249
R-Value Work: 0.155

logo
logo