OpenDEL™-Macrocycle

Starting Your Journey to Access Vast Chemical Space

 

The Kit

  • 1 Macrocycle Library and 1 Linear Control
  • ~230M compounds
  • 10 DEL samples
 

To Access

  • Fully enumerated molecules
  • Building Block Structures
  • DNA Codon Sequences
  • Scaffolds Information
 

✔ No Structure Disclosure Fee

 

✔ No Compound IP License Fee

Optional Services

OpenDEL™ Hit Proposal

Analyzing DEL selection data and choosing the right compounds for follow-up necessitates multidisciplinary expertise encompassing biology, computational science, and chemistry. This includes a deep understanding of the experimental design and mechanisms of action (MOAs) in biology, data processing and analysis in computational science, and aspects of both synthetic and DEL chemistry

OpenDEL™ Screening

OpenDEL™ screening is carried out by our team of experienced professionals, proficient in handling over 50 different target types including protein-protein interactions, kinases, enzymes, transcription factors, and RNA targets. Our team typically completes the screening experiments within 1-2 weeks. 

OpenDEL™ Sequencing

HitGen offers high-quality and gold sequencing service includes. 
  • Global Sample shipment

  • Outstanding sequencing quality

  • Lightning-speed result delivery

  • Diverse sequencing options

OpenDEL™ Off-DNA Synthesis

Our traditional synthesis service excels at recreating complex chemical structures derived from various DELs. We offer diverse options, including traditional chemistry synthesis service and high-throughput synthesis service. 
A. Traditional Chemical Synthesis @ HitGen 
B. High Throughput Chemical Synthesis @ HitGen‘s

Related resources

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OpenDEL™ 5.0 Flyer

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