Affinity selection and sequencing

Kit S. Lam
Nat. Chem. Biol., 2019, 15, 320-321
https://doi.org/10.1038/s41589-019-0253-2

Abstract

Powerful combinatorial peptide library methods allow the discovery of peptide leads from diverse libraries. A new platform based on tandem mass spectrometry peptide sequencing coupled with high-performance size-exclusion chromatography enables identification of high-affinity peptidic ligands from focused libraries.

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