Combinatorial libraries – from solution to 2D microarrays

Juan José Díaz-Mochón; Laurent Bialy; Lise Keinicke; Mark Bradley
Chem. Commun., 2005, 1384-1386
https://doi.org/10.1039/B415847D

Abstract

Enzymatic modifications of split and mix libraries were followed by “pulling down” onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library.

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