Lijun Xue; Hangke Ma; Weijie Liu; Nicolas Duchemin; Fanming Zeng; Jie Zhang; Huanqing Zhang; Kexin Yang; Yunjin Hu
ACS Omega, 2023, 8(26), 24072-24077
https://doi.org/10.1021/acsomega.3c03160

Abstract

A novel on-DNA oxidative disulfide formation method has been developed. Under ambient conditions, the methodology showcased wide applicability and swift implementation in routine DNA-encoded library synthesis to access pharmaceutically relevant motifs.