DNA-Compatible Conversion of Primary Amines into Azides

Dirk Trauner; Andrej Shemet
Synfacts, 2020, 16, 2, 0221
https://doi.org/10.1055/s-0039-1691634

Abstract

The researchers reported a robust, mild, and efficient protocol for the diazo-transfer reaction that works under aqueous conditions in the presence of DNA. This methodology proved to be suitable for the synthesis of DNA-encoded libraries.

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