Minsoo Song; Gil Tae Hwang
Nat. Chem., 2021, 13, 515–517
https://doi.org/10.1038/s41557-021-00690-6

Abstract

DNA-encoded libraries are a powerful tool to identify hit compounds for drug discovery. Now, two papers have reported new advances in this technology. One paper reports a method to screen for binders inside a living cell, and the other investigates the effects of stereo- and regiochemistry on ligand discovery.