DNA Microarrays as Decoding Tools in Combinatorial Chemistry and Chemical Biology

Marina Lovrinovic; Christof M. Niemeyer
Angew. Chem. Int. Ed. Engl., 2005, 44, 3179–3183
https://doi.org/10.1002/anie.200500645

Abstract

Decoding technology: Besides mainstream applications in transcription profiling, DNA microarrays are currently being explored as tools for the deconvolution of synthetic libraries. Current examples include the discovery of a new type of organic reaction and the screening of peptide nucleic acid encoded inhibitor libraries to investigate new proteolytic activities from dust mite extracts (see picture).

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