Encoded peptide libraries and the discovery of new cell binding ligands

Nina Svensen; Juan José Díaz-Mochón; Mark Bradley
Chem. Commun., 2011, 47, 7638-7640
https://doi.org/10.1039/C1CC11668A

Abstract

Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10 000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified

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