Zev J. Gartner; Matthew W. Kanan; David R. Liu
Angew. Chem. Int. Ed. Engl., 2002, 41(10), 1796-800
https://www.ncbi.nlm.nih.gov/pubmed/19750721

Abstract

Powerful reactions such as Wittig olefinations, nitro-aldol additions, dipolar cycloadditions, and Heck coupling reactions can be mediated by DNA templates. The yields of several DNA-templated reaction products are independent of the number of bases (n=0 or 10) separating the annealed reactive groups (as an example, the denaturing polyacrylamide gel electrophoresis of a DNA-templated Wittig reaction is shown).