Molecular Glues & Bifunctional Compounds: Therapeutic Modalities Based on Induced Proximity

Stuart Schreiber
ChemRxiv, 2024
https://doi.org/10.26434/chemrxiv-2024-q1n61

Abstract

This Perspective explores molecular glues and bifunctional compounds – proximity-inducing compounds – and offers a framework to understand and exploit their similarity to hot spots, missense mutations, and posttranslational modifications (PTMs).

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