Manuel Röthlingshöfer; Katarzyna Gorska; Nicolas Winssinger
Org. Lett., 2012, 14, 2, 482-485
https://doi.org/10.1021/ol203029t

Abstract

Hybridization-based reactions have attracted significant attention. The nucleic acid templated photocatalyzed azide reduction using catalytic amounts of a [Ru(bpy)(2)phen](2+) conjugate is reported. The reaction could be performed with as little as 2% of the Ru nucleic acid probe and was shown to productively unquench 7-azido-coumarin as well as uncage a small molecule.