Yue Zhang; Shengdi Xia; Wenxia Shi; Bizhen Lin; Xiaocan Su; Weiwei Lu; Xinyuan Wu; Xuan Wang; Xiaojie Lu; Ming Yan; Xuejing Zhang
Org. Lett., 2022, 24(43), 7961-7966
https://doi.org/10.1021/acs.orglett.2c03077

Abstract

The photocatalyst-free electron donor–acceptor (EDA) complex photochemistry was deemed to expand the potential of photodriven radical chemistry. Here, we report a cross-coupling reaction of thianthrenium salt functionalized arenes and sodium sulfinates via a photopromoted single electron transfer (SET) process of an EDA complex. A series of biarylsulfones were obtained with high site-selectivity and reactivity. This mild and practical radical reaction could be applied on the bioactive and DNA-encoded molecules.