Zachary Pastorel; Juliette Zanzi; Yves Canac; Olivier Baslé; Michael Smietana
Eur. J. Org. Chem., 2024, e202401297
https://doi.org/10.1002/ejoc.202401297

Abstract

Photochemistry has provided a powerful alternative to generate reactive intermediates under mild reaction conditions and photobiocatalysis is currently widely applied in organic synthesis. While enzyme-based photocatalysis has attracted a lot of attention, light-driven DNA-based biohybrid systems are also increasingly being applied to a large variety of applications from molecular imaging to enantioselective catalysis, and other fields such as DNA-encoded libraries (DELs). This review gives insights into these research fields by classifying the existing light-driven DNA-based biohybrid systems developed to date.