Setting GPCRs free - Nobel laureate Bob Lefkowitz discusses the future of G-protein-coupled receptor (GPCR)-targeted drug discovery

Asher Mullard
Nat. Rev. Drug Discov., 2023, 22, 347-348
https://doi.org/10.1038/d41573-023-00064-2

Abstract

Bob Lefkowitz has four quotes taped to the walls of his office at Duke University. “Life is filled with golden opportunities cleverly disguised as insoluble proteins,” reads the biochemist, before correcting the last words to “insolvable problems”.

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