Christian Heinis
Nat. Chem. Biol., 2014, 10(9), 696-8
https://doi.org/10.1038/nchembio.1605

Abstract

The application of macrocycles to previously undruggable targets has aroused a great deal of interest in this structural class. Recent studies advance our understanding of the way macrocycles bind protein targets and provide new strategies and tools to generate peptide-based macrocycles